Osteoclast Definition An osteoclast (plural “osteoclasts”) is a multinucleated cell found only in bones. It plays a crucial role in bone absorption and regeneration. Bone is a dynamic connective tissue … Read more
Osteoblast definition: Osteoblast (“Osteo” means bone & “blast” means formation) is a uni-nucleated cell, produced from pluripotent mesenchymal stem cells. Osteoblast’s function is essential for mineralization and synthesis of bone … Read more
The bone remodeling process is crucial for maintaining the balance in the metabolic changes between bone formation and bone resorption. Two specialized cells, such as osteoblast and osteoclast, are responsible … Read more
Cancer is a type of disease, in which uncontrollable cell growth of an organ or circulatory cells can be recognized, anywhere in the body, if any mutations take place at … Read more
Thermogenin Definition Thermogenin is an uncoupling protein found in the plasma membrane of prokaryotes and the inner membrane of mitochondria of both plants and animal cells. Uncoupling protein is involved … Read more
Ubiquitination definition Ubiquitination is a post-translational modification process that plays a major role in protein degradation. The ubiquitin-proteasome system is involved in the process called ubiquitination, ubiquitylation, or molecular “kiss … Read more
Autophagy definition Autophagy (“auto” means self and “phagy” means eating) is the major non-apoptotic degradation pathway in eukaryotic cells and is required for the elimination of damaged organelles, proteins, and … Read more
Definition of lysosomal storage disease The lack of functional enzymes to regulate the excessive accumulation of their respective substrates has led to the emergence of genetic conditions known as lysosomal … Read more
Proteasome Definition The proteasome is a protein complex that plays a crucial role in maintaining the cellular homeostasis by degrading the misfolded or damaged protein molecules. Proteasome complex is involved … Read more
Marker enzymes definition: Marker enzymes are biomarkers, which are not frequent but limited to and synthesized by specific cell organelles. Hence, the marker enzymes are used to find and isolate … Read more